منابع مشابه
Phase Separation in Multicomponent Aqueous-Protein Solutions
published in Advance ACS Abstracts, December 1, 1994. 0022-3654/95/2099-0454$09.00/0 we present here the results of experimental and theoretical studies of a ternary solution constituted of the proteins yma (designated as protein A), a “high-Tc” protein, and yw (designated as protein B), a “low-Tc” protein, in aqueous solution. The solution pH was kept constant at 7.1 by a 100 mM phosphate buff...
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Faithful chromosome segregation entails long-range chromosome movement into newly dividing cells. A recent study implicates CDK1 function in releasing mitotic telomeres from the nuclear envelope, thereby liberating chromosomes for mitotic segregation.
متن کاملAqueous two-phase systems for protein separation: phase separation and applications.
Aqueous two-phase systems (ATPS) that are formed by mixing a polymer (usually polyethylene glycol, PEG) and a salt (e.g. phosphate, sulphate or citrate) or two polymers, and water can be effectively used for the separation and purification of proteins. The partitioning between both phases is dependent on the surface properties of the proteins and on the composition of the two phase system as ha...
متن کاملMonte Carlo study of phase separation in aqueous protein solutions
The binary liquid phase separation of aqueous solutions of g-crystallins is utilized to gain insight into the microscopic interactions between these proteins. The interactions are modeled by a square-well potential with reduced range l and depth e . A comparison is made between the experimentally determined phase diagram and the results of a modified Monte Carlo procedure which combines simulat...
متن کاملSelf-crowding induced phase separation in protein dispersions.
The coupling between protein conformation, molecular volume, and solution phase behaviour is studied theoretically for a two-state, coarse-grained protein model in which protein molecules can reversibly switch between a native and a non-native excited state. In the model, native and non-native conformers are represented by perfect spheres with different hard-core diameters. We presume the large...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2019
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2019.04.011